Brisbanes river walk is one of the most relaxing walks you can do, with views of Southbank, the CBD and the flowing river!
The path itself is always jam packed full of tourists trying to take the best shot, or of families or workers g tting from point a to point b, as it connects the city to Southbank and then beyond. There are many stops along the way if you want a bite to eat or even stop off for a shop or to see a movie.
This is also a great idea if you're visiting and want to fit some fitness into your schedule, workout with a view!
There are also many forms of public transport, trains, bus and ferry, that can get you to and from both starting points, as well as many car parks along the way.

My recommendation is starting in the CBD and ending at Southbank, that's where most of the views are!